Early-Onset Alzheimer’s Disease

Release: June 15, 2021
Expiration: June 15, 2023


Nick Fox is a professor of Clinical Neurology, the director of the Dementia Research Centre at the University College London’s Institute of Neurology and a group leader in the U.K. Dementia Research Institute. He is also a consultant neurologist at the National Hospital for Neurology and Neurosurgery, Queen Square, London. His first degree was in physics and physiology at the University of Cambridge. He subsequently studied medicine at the University of London, specializing in cognitive neurology.

Fox runs a specialist cognitive disorders clinic and has long-standing clinical and research interests in younger-onset and familial dementias. He has been involved in dementia research for over 20 years, with particular interests in improving diagnosis and using imaging and other biomarkers to accelerate the search for effective therapies. Techniques that he developed to track disease progression using serial MRI have been used in more than 20 international clinical trials. He has contributed to a number of multimodal national and international longitudinal cohort studies in sporadic and familial Alzheimer’s disease and related disorders.

Fox has published over 450 papers and is a Web of Science Group highly cited researcher, ranking in the top 1% by citations. He is a member of the Alzheimer’s Society Research Strategy Council and was a member of the U.K. Prime Minister’s Dementia Research Champion’s Group. He received the 2017 Weston Brain Institute International Outstanding Achievement Award.

Sponsorship This is an Alzheimer’s Association activity
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Alzheimer's Association is a not-for-profit 501(c)(3) organization.
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All materials are included with permission. The opinions expressed are those of the faculty and are not to be construed as those of the publisher.

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.

This CME/CE activity might describe the off-label, investigational, or experimental use of medications that may exceed their FDA- approved labeling. Physicians should consult the current manufacturers’ prescribing information for these products. ACHL requires the speaker to disclose that a product is not labeled for the use under discussion.

Target Audience / Intended Audience This activity is intended to meet the educational needs of primary care clinicians including internists, family physicians, radiologists, neurologists, nurse practitioners and physician assistants who are seeking additional education in the assessment, diagnosis and ongoing health care of patients with cognitive impairment and dementia.
Statement of Need / Activity Purpose

Attendees will be introduced to various research aspects of Alzheimer’s Disease and related dementias.

Learning Objectives

During this session you will learn:

  • Describe the prevalence of early-onset Alzheimer's disease
  • Identify and evaluate the potential differences in clinical presentation for early-onset AD
  • Understand the role of genetics in EOAD 
Method of Participation

This curriculum will take approximately 60 minutes to complete.

In order to obtain your CE certificate, please follow the steps below at the conclusion of the activity:

  1. Go to cmeuniversity.com
  2. Login or Create a New Account (will take less than 1 minute)
    If you receive a message when creating a new account that “the email you entered is already in use”, please click the Forgot my Username or Password link to have your Username and Password sent to you via email

  3. After logging in, you may be asked to verify/update your information; after doing so, click Save at the bottom of the page
  4. Type in 16486 at the top of the page, “Find Post-Test/Evaluation by Course”, and click enter
  5. Click on the activity title when it appears
  6. Choose the type of credit you desire
  7. Complete the online Evaluation
  8. Receive an immediate CE Certificate to download and/or print for your files

If you have questions regarding the certification of this activity, please contact PIM via email at inquiries@pimed.com

Joint Providership Accreditation Statement In support of improving patient care, this activity has been planned and implemented by the Postgraduate Institute for Medicine and the Alzheimer’s Association. Postgraduate Institute for Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Credit Designation

Physician Continuing Medical Education
The Postgraduate Institute for Medicine designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Continuing Nursing Education
The maximum number of hours awarded for this Continuing Nursing Education activity is 1.0 contact hours.

Continuing Psychologist Education
Continuing Education (CE) credits for psychologists are provided through the co-sponsorship of the American Psychological Association (APA) Office of Continuing Education in Psychology (CEP). The APA CEP Office maintains responsibility for the content of the programs.

Credit Designation- This program offers 1.0 continuing education credits for psychologists.

Continuing Social Work Education

As a Jointly Accredited Organization, Postgraduate Institute for Medicine is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. State and provincial regulatory boards have the final authority to determine whether an individual course may be accepted for continuing education credit. Postgraduate Institute for Medicine maintains responsibility for this course. Social workers completing this course receive 1.0 Clinical continuing education credits.

Faculty Disclosures

Postgraduate Institute for Medicine (PIM) requires faculty, planners, and others in control of educational content to disclose all their financial relationships with ineligible companies. All identified conflicts of interest (COI) are thoroughly vetted and mitigated according to PIM policy. PIM is committed to providing its learners with high quality accredited continuing education activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

The faculty reported the following relevant financial relationships with ineligible entities related to the educational content of this CME/ CE program:

Faculty Name and Degree(s)

Dr. Nick Fox has nothing to disclose.
The PIM planners and others have nothing to disclose. The AA planners and others have nothing to disclose.

Hardware and Software Requirements 

Hardware/Software Requirement:

  1. Active internet connection (DSL or Cable). Dial-up connection will have constant buffering problems while viewing any media (audio/video).
  2. Compatible with Windows PC and MAC (256 MB of RAM or higher)
    • Windows OS 7.0 and higher.
    • MAC OS “Mountain Lion” and higher.
  3. Activity is best viewed on Internet Explorer 9.0 or higher, Safari 5.0 or higher and Firefox 40.0 or higher
  4. Peripherals: Speakers for audio.
  5. Adobe Reader to print certificate. Click here to download Adobe Reader for free.