Educational Workshop: The Basics of Fluid Biomarkers in Alzheimer’s Disease (Day 4)

Recorded: July 1, 2021

The fluid biomarkers field for Alzheimer’s disease (AD) and other dementias is rapidly expanding. This workshop provides research investigators, clinicians, residents, fellows and graduate and postgraduate students with an in-depth understanding of the fundamental principles, inherent limitations and clinical and research applications of the most common biomarkers used in AD and found in cerebrospinal fluid (CSF) and blood. This workshop includes the fundamentals of CSF physiology, basics of neurochemistry, technical issues of sample collection, storage, analysis methods, quality control and regulatory issues. It also covers the latest in cutting-edge biomarker technology including blood-based biomarkers with the current understanding of how biomarkers track the progression in AD and their use in other dementias. Lectures are followed by interactive Q&A sessions to ensure that participants gain an in-depth understanding of the proper use of fluid biomarkers.

This workshop was organized by leading scientists in this field and by the Alzheimer’s Association Global Biomarkers Standardization Consortia (GBSC) and the ISTAART Biofluid Based Biomarkers PIA.

In this fourth part of the workshop, Jonathan Schott discusses the "Current Context of Use of Fluid Biomarkers for AD and Differential Diagnosis in Dementia (case-based approach)" and Charlotte Teunissen discusses the "State of the Art and Potential of Omics Biomarkers in Biofluids".