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NIA-AA Symposium: Enabling Precision Medicine for Alzheimer’s Disease Through Open Science

The NIA-AA Symposium: Enabling Precision Medicine for Alzheimer's Disease for Alzheimer's Disease Through Open Science features an array of NIA-supported translational dementia research programs that employ precision medicine principles and open-science practices to

  • Understand the complex and heterogeneous etiology of Alzheimer’s.
  • Identify new disease-relevant targets and biomarkers.
  • Develop the next generation animal models for late onset AD.
  • Advance novel targets into drug discovery by developing target enabling research tools.

Session 1: AMP AD – Precision Medicine Approach to Novel Target and Biomarker Discovery

Recorded October 27, 2021

Session 1: AMP AD – Precision Medicine Approach to Novel Target and Biomarker Discovery

Co-chairs:
Nilüfer Ertekin-Taner, Matthias Arnold

Panelists:
Bin Zhang, Laura Heath, Phil De Jager, Lenora Ann Higginbotham

Session 2: MODEL-AD Consortium – A Precision Medicine Approach to the Development of Animal Models of Late Onset AD and Preclinical Efficacy Testing

Recorded October 27, 2021

Session 2: MODEL-AD Consortium – A Precision Medicine Approach to the Development of Animal Models of Late Onset AD and Preclinical Efficacy Testing

Co-chairs:
Bruce Lamb, Andrea Tenner

Panelists:
Greg Carter, Gareth Howell, Adrian Oblak, Paul Territo, Stacey Rizzo, Ali Mortazavi, Kim Green

Session 3: TREAT-AD Centers – Expanding the AD Target Landscape and Accelerating Drug Discovery for Novel Targets

Recorded October 27, 2021

Session 3: TREAT-AD Centers – Expanding the AD Target Landscape and Accelerating Drug Discovery for Novel Targets

Co-chairs:
Alan Palkowitz, Lara Mangravite

Panelists:
Timothy Richardson, Andrew Mesecar, Lara Mangravite, Nick Seyfried, Haian Fu

Session 4: Alzheimer’s Gut Microbiome Project

Recorded October 28, 2021

Session 4: Alzheimer’s Gut Microbiome Project

Co-chairs:
Rima Kaddurah-Daouk, Sarkis Mazmanian

Panelists:
Rob Knight, Sarkis Mazmanian, Gabi Kastenmuller

Session 5: Impact of Sex Differences on the Molecular Determinants of AD Risk and Resilience and Responsiveness to Treatment

Recorded October 28, 2021

Session 5: Impact of Sex Differences on the Molecular Determinants of AD Risk and Resilience and Responsiveness to Treatment

Co-chairs:
Catherine Kaczorowski, Susan Catalano

Panelists:
Carol Colton, Dena Dubal, Marina Sirota, Ivan Nalvarte

Session 6: Precision Medicine Cohorts and Consortia – ABC-DS, HABS-HD, LEADS

Recorded October 28, 2021

Session 6: Precision Medicine Cohorts and Consortia – ABC-DS, HABS-HD, LEADS

Co-chairs:
Sid O’Bryant, Liana Apostolova

Panelists:
ABC-DS: Liz Head, Annie Cohen, Mark Mapstone
HABS-HD: Sid O’Bryant
LEADS: Liana Apostolova