DaDA PIA: Cascading Epigenomic Analysis for GWAS

Recorded: January 20, 2021

This event presents a new multi-omic integration method, CEWAS, that models the cascading effects of SNPs from epigenome to transcriptome and eventually to the phenome for identifying disease genes from GWAS. We show on sixteen brain-related GWAS that CEWAS provides a higher gene detection rate than related methods, and finds less explored disease relevant genes and gene sets.

Panelist: Bernard Ng